Differential Effects of HOXB4 on Nonhuman Primate Short- and Long-Term Repopulating Cells
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چکیده
منابع مشابه
Differential Effects of HOXB4 on Nonhuman Primate Short- and Long-Term Repopulating Cells
BACKGROUND Hematopoietic stem cells (HSCs) or repopulating cells are able to self-renew and differentiate into cells of all hematopoietic lineages, and they can be enriched using the CD34 cell surface marker. Because of this unique property, HSCs have been used for HSC transplantation and gene therapy applications. However, the inability to expand HSCs has been a significant limitation for clin...
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ژورنال
عنوان ژورنال: PLoS Medicine
سال: 2006
ISSN: 1549-1676
DOI: 10.1371/journal.pmed.0030173